Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but They're unusual On this malignancy when compared with other lymphoid neoplasms. CHD2 is mutated in 5% of CLL and 7% of MBL.75 The histone methyltransferase SETD2 and ARID1A may also be mutated in a small proportion of people. Of Notice, MYD88 mutations